关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称： 兔抗ULBP1多克隆抗体
英文名称：Anti-ULBP1 rabbit polyclonal antibody
别 名： RAET1I
相关类别：一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： ULBP1
反应种属：Human
标 记 物：Unconjugate
克隆类型：rabbit polyclonal
技术规格
Background: | Ligand for the KLRK1/NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. |
Applications: | ELISA, IHC |
Name of antibody: | ULBP1 |
Immunogen: | Synthetic peptide of humanULBP1 |
Full name: | UL16 binding protein 1 |
Synonyms： | RAET1I |
SwissProt: | Q9BZM6 |
ELISA Recommended dilution: | 2000-5000 |
IHC positive control: | Human breast cancer |
IHC Recommend dilution: | 25-100 |
上海通蔚实业有限公司位于中国率先大城市——人民共和国直辖市之一的上海，且依托上海张江高科生物研究优势，主要是一家经营elisa试剂盒、检测试剂盒、酶联检测试剂盒等产品的厂家，目前已发展成集科研、生产、销售为一体的创新性企业。
